Team 2 – Biology and Pharmacology of Cardiovascular Remodeling

Team headed by F. Soubrier

Team 2 focuses its research on understanding the molecular and cellular mechanisms involved in cardiac and vascular remodeling under pathological conditions. This team combines gene transfer using viral vectors, transgenic animal models, important human bioressources and strong interactions with physicians and partners from the industry to develop a translational research.

This team is attached to the “école doctorale” 394 “Physiologie et Physiopathologie”.

 

Team 3 – Pathophysiology of Cellular Excitability

Team 3 is headed by S. Hatem.

Team 3 focuses its research program on the identification of molecular mechanisms underlying cardiac ion channel trafficking and their role in the pathophysiology of cardiac arrhythmias with a strong emphasis on atrial fibrillation. Using cardiac myocyte electrophysiology, molecular imaging of living cells and experimental models of cardiac diseases, team 3 studies the mechanisms underlying cardiac remodeling, atrial excitability modifications and the substrate of atrial fibrillation.

This team is attached to the “école doctorale” 394 “Physiologie et Physiopathologie”.