Team 4 publications

Team 4 publications (2015-)

  1. Gomez Rosso L, Lhomme M, Meroño T, Dellepiane A, Sorroche P, Hedjazi L, Zakiev E, Sukhorukov V, Orekhov A, Gasparri J, Chapman MJ, Brites F, Kontush A. Poor glycemic control in type 2 diabetes enhances functional and compositional alterations of small, dense HDL3c. Biochim Biophys Acta. 2017 Feb;1862(2):188-195.
  2. Menezes S, Melandri D, Anselmi G, Perchet T, Loschko J, Dubrot J, Patel R, Gautier EL, Hugues S, Longhi MP, Henry JY, Quezada SA, Lauvau G, Lennon-Duménil AM, Gutiérrez-Martínez E, Bessis A, Gomez-Perdiguero E, Jacome-Galarza CE, Garner H, Geissmann F, Golub R, Nussenzweig MC, Guermonprez P. The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic CellsImmunity. 2016 Dec 20;45(6):1205-1218.
  3. Buttgereit A, Lelios I, Yu X, Vrohlings M, Krakoski NR, Gautier EL, Nishinakamura R, Becher B, Greter M. Sall1 is a transcriptional regulator defining microglia identity and functionNat Immunol. 2016 Dec;17(12):1397-1406.
  4. Orsoni A, Thérond P, Tan R, Giral P, Robillard P, Kontush A, Meikle PJ, Chapman MJ. Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia. J Lipid Res. 2016 Nov;57(11):2073-2087.
  5. Hansel B, Bonnefont-Rousselot D, Orsoni A, Bittar R, Giral P, Roussel R, Marre M, Mohammedi K, Bruckert E, Chapman MJ, Kontush A. Lifestyle intervention enhances high-density lipoprotein function among patients with metabolic syndrome only at normal low-density lipoprotein cholesterol plasma levels. J Clin Lipidol. 2016 Sep-Oct;10(5):1172-81.
  6. Didichenko SA, Navdaev AV, Cukier AM, Gille A, Schuetz P, Spycher MO, Thérond P, Chapman MJ, Kontush A, Wright SD. Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity. Circ Res. 2016 Sep 2;119(6):751-63.
  7. Filou S, Lhomme M, Karavia EA, Kalogeropoulou C, Theodoropoulos V, Zvintzou E, Sakellaropoulos GC, Petropoulou PI, Constantinou C, Kontush A, Kypreos KE. Distinct Roles of Apolipoproteins A1 and E in the Modulation of High-Density Lipoprotein Composition and FunctionBiochemistry2016 Jul 12;55(27):3752-62.
  8. Codoni V, Blum Y, Civelek M, Proust C, Franzén O, Björkegren JL, Le Goff W, Cambien F, Lusis AJ, Trégouët DA. Preservation analysis of macrophage gene co-expression between human and mouse identifies PARK2 as a genetically controlled master regulator of oxydative phosphorylation in humans. Genes/Genomes/Genetics 2016 Aug 24.
  9. Kim KW, Williams JW, Wang YT, Ivanov S, Gilfillan S, Colonna M, Virgin HW, Gautier EL, Randolph GJ. MHC II+ résident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytesJ Exp Med. 2016 Aug 22.
  10. Le Goff C, Rogers C, Le Goff W, Pinto G, Bonnet D, Chrabieh M, Alibeu O, Nistchke P, Munnich A, Picard C, Cormier-Daire V. Heterozygous Mutations in MAP3K7, Encoding TGF-β-Activated Kinase 1, Cause Cardiospondylocarpofacial SyndromeAm J Hum Genet. 2016 Aug 4;99(2):407-13.
  11. Borradaile N, Le Goff W. Lipidomic approach provides new clues toward solving the mystery of accelerated atherosclerosis in diabetesAtherosclerosis. 2016 Aug;251:507.
  12. Kim KW, Williams JW, Wang YT, Ivanov S, Gilfillan S, Colonna M, Virgin HW, Gautier EL, Randolph GJ. MHC II+ résident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes. J Exp Med. 2016 Aug 22.
  13. Le Goff C, Rogers C, Le Goff W, Pinto G, Bonnet D, Chrabieh M, Alibeu O, Nistchke P, Munnich A, Picard C, Cormier-Daire V. Heterozygous Mutations in MAP3K7, Encoding TGF-β-Activated Kinase 1, Cause Cardiospondylocarpofacial Syndrome. Am J Hum Genet. 2016 Aug 4;99(2):407-13.
  14. Borradaile N, Le Goff W. Lipidomic approach provides new clues toward solving the mystery of accelerated atherosclerosis in diabetes. Atherosclerosis. 2016 Aug;251:507.
  15. Darabi M, Kontush A. Phosphatidylserine in atherosclerosis. Curr Opin Lipidol. 2016 Apr 8.
  16. Zanoni P, Khetarpal SA, Larach DB, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A, Surendran P, Saleheen D, Trompet S, Jukema JW, De Craen A, Deloukas P, Sattar N, Ford I, Packard C, Majumder Aa, Alam DS, Di Angelantonio E, Abecasis G, Chowdhury R, Erdmann J, Nordestgaard BG, Nielsen SF, Tybjærg-Hansen A, Schmidt RF, Kuulasmaa K, Liu DJ, Perola M, Blankenberg S, Salomaa V, Männistö S, Amouyel P, Arveiler D, Ferrieres J, Müller-Nurasyid M, Ferrario M, Kee F, Willer CJ, Samani N, Schunkert H, Butterworth AS, Howson JM, Peloso GM, Stitziel NO, Danesh J, Kathiresan S, Rader DJ; CHD Exome+ Consortium; CARDIoGRAM Exome Consortium; Global Lipids Genetics Consortium. Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science. 2016 Mar 11;351(6278):1166-71. 
  17. Kontush A. Identifying new Risk Markers and Potential Targets: The Value of the Proteome. Cardiovasc Drugs Ther. 2016 Feb;30(1):13-18.
  18. Meroño T, Dauteuille C, Teztlaff W, Martín M, Botta E, Lhomme M, Saez MS, Sorroche P, Boero L, Arbelbide J, Chapman MJ, Kontush A, Brites F. Oxidative stress, HDL functionality and effects of intravenous iron administration in women with iron deficiency anemia. Clin Nutr. 2016 Feb 13.
  19. Ivanov S, Scallan JP, Kim KW, Werth K, Johnson MW, Saunders BT, Wang PL, Kuan EL, Straub AC, Ouhachi M, Weinstein EG, Williams JW, Briseño C, Colonna M, Isakson BE, Gautier EL, Förster R, Davis MJ, Zinselmeyer BH, Randolph GJ. CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability. J Clin Invest. 2016 Apr 1;126(4):1581-91.
  20. Sarrazy V, Viaud M, Westerterp M, Ivanov S, Giorgetti-Peraldi S, Guinamard R, Gautier EL, Thorp EB, De Vivo DC, Yvan-Charvet L. Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE-/- Mice. Circ Res. 2016 Apr 1;118(7):1062-77.
  21. Valleix S, Verona G, Jourde-Chiche N, et al. D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile. Nat Commun. 2016;7:10353.
  22. Rosenson RS, Brewer HB, Jr., Ansell BJ, Barter P, Chapman MJ, Heinecke JW, Kontush A, Tall AR and Webb NR. Dysfunctional HDL and atherosclerotic cardiovascular disease. Nat Rev Cardiol. 2016; 13: 48-60.
  23. Potiron A, Gerard P, Le Roy T, Lesnik P, Maguin E and Rhimi M. Recent Patents on Hypocholesterolemic Therapeutic Strategies: An Update. Recent Adv DNA Gene Seq. 2016; 9: 36-44.
  24. Mancia G, Omboni S, Chazova I, Coca A, Girerd X, Haller H, Parati G, Pauletto P, Pupek-Musialik D, Svyshchenko Y and Group FS. Effects of the lercanidipine-enalapril combination vs. the corresponding monotherapies on home blood pressure in hypertension: evidence from a large database. J Hypertens. 2016; 34: 139-48.
  25. Lhermusier T, Severin S, Van Rothem J, Garcia C, Bertrand-Michel J, Le Faouder P, Hechler B, Broccardo C, Couvert P, Chimini G, Sie P and Payrastre B. ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces TXA2 production independently of hematopoietic ABCA1. J Thromb Haemost. 2016.
  26. Le Clanche S, Bonnefont-Rousselot D, Sari-Ali E, Rannou F and Borderie D. Inter-relations between osteoarthritis and metabolic syndrome: A common link? Biochimie. 2016;121:238-52.
  27. Jacobsen MJ, Mentzel CM, Olesen AS, Huby T, Jorgensen CB, Barres R, Fredholm M and Simar D. Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity. J Diabetes Res. 2016; 2016: 8539057.
  28. Hamy AS, Porcher R, Eskenazi S, Cuvier C, Giacchetti S, Coussy F, Hocini H, Tournant B, Perret F, Bonfils S, Charveriat P, Lacorte JM and Espie M. Anti-Mullerian hormone in breast cancer patients treated with chemotherapy: a retrospective evaluation of subsequent pregnancies. Reprod Biomed Online. 2016.
  29. Giral P, Hansel B and Chapman J. Dual Lipid-Lowering Strategy With Ezetimibe and Atorvastatin on Coronary Plaque Regression After PCI: PRECISE-IVUS. J Am Coll Cardiol. 2016; 67: 234.
  30. El Khoury P, Waldmann E, Huby T, Gall J, Couvert P, Lacorte JM, Chapman J, Frisdal E, Lesnik P, Parhofer KG, Le Goff W and Guerin M. Extended-Release Niacin/Laropiprant Improves Overall Efficacy of Postprandial Reverse Cholesterol Transport. Arterioscler Thromb Vasc Biol. 2016; 36: 285-94.
  31. Denolle T, Chamontin B, Doll G, Fauvel JP, Girerd X, Herpin D, Vaisse B, Villeneuve F and Halimi JM. Management of resistant hypertension: expert consensus statement from the French Society of Hypertension, an affiliate of the French Society of Cardiology. J Hum Hypertens. 2016.
  32. Darabi M and Kontush A. Can phosphatidylserine enhance atheroprotective activities of high-density lipoprotein? Biochimie. 2016; 120: 81-6.
  33. Darabi M, Guillas-Baudouin I, Le Goff W, Chapman MJ and Kontush A. Therapeutic applications of reconstituted HDL: When structure meets function. Pharmacol Ther. 2016; 157: 28-42.
  34. Tussiwand R and Gautier EL. Transcriptional Regulation of Mononuclear Phagocyte Development. Front Immunol. 2015; 6: 533.
  35. Szalat R, Monsel G, Le Goff W, Battistella M, Bengouffa D, Schlageter MH, Bouaziz JD, Arnulf B, Vignon M, Lesnik P, Saussine A, Malphettes M, Lazareth A, Vignon-Pennamen MD, Bagot M, Brouet JC, Fermand JP, Rybojad M and Asli B. The spectrum of neutrophilic dermatoses associated with monoclonal gammopathy: Association with IgA isotype and inflammatory profile. J Am Acad Dermatol. 2015; 73: 809-20.
  36. Silveira A, McLeod O, Strawbridge RJ, Gertow K, Sennblad B, Baldassarre D, Veglia F, Deleskog A, Persson J, Leander K, Gigante B, Kauhanen J, Rauramaa R, Smit AJ, Mannarino E, Giral P, Gustafsson S, Soderberg S, Ohrvik J, Humphries SE, Tremoli E, de Faire U and Hamsten A. Plasma IL-5 concentration and subclinical carotid atherosclerosis. Atherosclerosis. 2015; 239: 125-30.
  37. Sarrazy V, Sore S, Viaud M, Rignol G, Westerterp M, Ceppo F, Tanti JF, Guinamard R, Gautier EL and Yvan-Charvet L. Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation. Cell Rep. 2015; 13: 132-44.
  38. Repetto E, Lichtenstein L, Hizir Z, Tekaya N, Benahmed M, Ruidavets JB, Zaragosi LE, Perret B, Bouchareychas L, Genoux A, Lotte R, Ruimy R, Ferrieres J, Barbry P, Martinez LO and Trabucchi M. RNY-derived small RNAs as a signature of coronary artery disease. BMC Med. 2015; 13: 259.
  39. Rambhojan C, Bouaziz-Amar E, Larifla L, Deloumeaux J, Clepier J, Plumasseau J, Lacorte JM and Foucan L. Ghrelin, adipokines, metabolic factors in relation with weight status in school-children and results of a 1-year lifestyle intervention program. Nutr Metab (Lond). 2015; 12: 43.
  40. Rached FH, Chapman MJ and Kontush A. HDL particle subpopulations: Focus on biological function. Biofactors. 2015; 41: 67-77.
  41. Rached F, Lhomme M, Camont L, Gomes F, Dauteuille C, Robillard P, Santos RD, Lesnik P, Serrano CV, Jr., Chapman MJ and Kontush A. Defective functionality of small, dense HDL3 subpopulations in ST segment elevation myocardial infarction: Relevance of enrichment in lysophosphatidylcholine, phosphatidic acid and serum amyloid ABiochim Biophys Acta. 2015; 1851: 1254-61.
  42. Picard HL, Thurairajasingam N, Decramer S, Girerd X, Oshaugnessy K, Mulatero P, Roussey G, Tack I, Unwin R, Vargas-Poussou R and Jeunemaitre X. Mutations Affecting the Conserved Acidic Motif of Wnk1 Cause Inherited Normotensive Hyperkalemic AcidosisJ Hypertens. 2015; 33 Suppl 1:e1.
  43. Persson J, Strawbridge RJ, McLeod O, et al. Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular DiseaseJ Am Heart Assoc. 2015; 4: e001853.
  44. Pant SD, Karlskov-Mortensen P, Jacobsen MJ, Cirera S, Kogelman LJ, Bruun CS, Mark T, Jorgensen CB, Grarup N, Appel EV, Galjatovic EA, Hansen T, Pedersen O, Guerin M, Huby T, Lesnik P, Meuwissen TH, Kadarmideen HN and Fredholm M. Comparative Analyses of QTLs Influencing Obesity and Metabolic Phenotypes in Pigs and HumansPloS one. 2015; 10: e0137356.
  45. Napal S and Giral PJ. Are we moving towards the end of the prostate specific antigen era? Actas Urol Esp. 2015; 39: 593.
  46. Moren X, Lhomme M, Bulla A, Sanchez JC, Kontush A and James RW. Proteomic and lipidomic analyses of paraoxonase defined high density lipoprotein particles: association of paraoxonase with the anti-coagulant, protein SProteomics Clin Appl. 2015.
  47. Monneret D, Mestari F, Atlan G, Corlouer C, Ramani Z, Jaffre J, Dever S, Fressart V, Alkouri R, Lamari F, Devilliers C, Imbert-Bismut F and Bonnefont-Rousselot D. Hemolysis indexes for biochemical tests and immunoassays on Roche analyzers: determination of allowable interference limits according to different calculation methods. Scand J Clin Lab Invest. 2015; 75: 162-9.
  48. Monneret D, Devilliers C and Bonnefont-Rousselot D. Comparison of measured venous carbon dioxide and calculated arterial bicarbonates according to the PaCO2 and PaO2 cut-off values of obesity hypoventilation syndromeClin Chem Lab Med. 2015; 53: e343-6.
  49. Monneret D, Corlouer C, Bigot J, Atlan G, Alkouri R, Mestari F, Dever S, Imbert-Bismut F and Bonnefont-Rousselot D. Comparison of a 10- vs. 15-min centrifugation time for chemical and immunochemical assays and impact on turnaround time in a hospital laboratoryClin Chem Lab Med. 2015.
  50. Monneret D, Bonnefont-Rousselot D and Roche F. Letter by Monneret et al Regarding Article, “Cardiac Structure and Function Across the Glycemic Spectrum in Elderly Men and Women Free of Prevalent Heart Disease: The Atherosclerosis Risk In the Community Study”Circ Heart Fail. 2015; 8: 1009.
  51. Moinard C, Le Plenier S, Noirez P, Morio B, Bonnefont-Rousselot D, Kharchi C, Ferry A, Neveux N, Cynober L and Raynaud-Simon A. Citrulline Supplementation Induces Changes in Body Composition and Limits Age-Related Metabolic Changes in Healthy Male RatsThe Journal of nutrition. 2015; 145: 1429-37.
  52. Merono T, Brites F, Dauteuille C, Lhomme M, Menafra M, Arteaga A, Castro M, Saez MS, Ballerga EG, Sorroche P, Rey J, Lesnik P, Sorda JA, Chapman MJ, Kontush A and Daruich J. Metabolic alterations, HFE gene mutations and atherogenic lipoprotein modifications in patients with primary iron overloadClinical science. 2015; 128: 609-18.
  53. Meikle PJ, Wong G, Tan R, Giral P, Robillard P, Orsoni A, Hounslow N, Magliano DJ, Shaw JE, Curran JE, Blangero J, Kingwell BA and Chapman MJ. Statin action favors normalization of the plasma lipidome in the atherogenic mixed dyslipidemia of MetS: potential relevance to statin-associated dysglycemiaJournal of lipid research. 2015; 56: 2381-92.
  54. Mavromati M, Amsallem M, Jublanc C, Bruckert E, Leenhardt L and Girerd X. Questioning the pathogenic role of the pTyr791Phe mutation of the RET proto-oncogene: Insight from a case reportAnn Endocrinol (Paris). 2015; 76: 690-4.
  55. Kontush A, Lindahl M, Lhomme M, Calabresi L, Chapman MJ and Davidson WS. Structure of HDL: particle subclasses and molecular componentsHandb Exp Pharmacol. 2015; 224: 3-51.
  56. Kontush A. HDL particle number and size as predictors of cardiovascular diseaseFront Pharmacol. 2015; 6: 218.
  57. Karlsson H, Kontush A and James RW. Functionality of HDL: antioxidation and detoxifying effectsHandb Exp Pharmacol. 2015; 224: 207-28.
  58. Jiang C, Carillion A, Na N, De Jong A, Feldman S, Lacorte JM, Bonnefont-Rousselot D, Riou B and Amour J. Modification of the beta-Adrenoceptor Stimulation Pathway in Zucker Obese and Obese Diabetic Rat MyocardiumCrit Care Med. 2015; 43: e241-9.
  59. Huvenne H, Le Beyec J, Pepin D, Alili R, Kherchiche PP, Jeannic E, Frelut ML, Lacorte JM, Nicolino M, Viard A, Laville M, Ledoux S, Tounian P, Poitou C, Dubern B and Clement K. Seven novel deleterious LEPR mutations found in early-onset obesity: a DeltaExon6-8 shared by subjects from Reunion Island, France, suggests a founder effectJ Clin Endocrinol Metab. 2015; 100: E757-66.
  60. Hopkins PN, Defesche J, Fouchier SW, et al. Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal AntibodyCirc Cardiovasc Genet. 2015; 8: 823-31.
  61. Hescot S, Seck A, Guerin M, Cockenpot F, Huby T, Broutin S, Young J, Paci A, Baudin E and Lombes M. Lipoprotein-Free Mitotane Exerts High Cytotoxic Activity in Adrenocortical CarcinomaJ Clin Endocrinol Metab. 2015; 100: 2890-8.
  62. Hansel B, Roussel R, Diguet V, Deplaude A, Chapman MJ and Bruckert E. Relationships between consumption of alcoholic beverages and healthy foods: the French supermarket cohort of 196,000 subjectsEur J Prev Cardiol. 2015; 22: 215-22.
  63. Gandolfini MP, Coupaye M, Bouaziz E, Dehoux M, Hajage D, Lacorte JM and Ledoux S. Cardiovascular Changes After Gastric Bypass Surgery: Involvement of Increased Secretions of Glucagon-Like Peptide-1 and Brain Natriuretic PeptideObes Surg. 2015; 25: 1933-9.
  64. Frisdal E, Le Lay S, Hooton H, Poupel L, Olivier M, Alili R, Plengpanich W, Villard EF, Gilibert S, Lhomme M, Superville A, Miftah-Alkhair L, Chapman MJ, Dallinga-Thie GM, Venteclef N, Poitou C, Tordjman J, Lesnik P, Kontush A, Huby T, Dugail I, Clement K, Guerin M and Le Goff W. Adipocyte ATP-binding cassette G1 promotes triglyceride storage, fat mass growth, and human obesityDiabetes. 2015; 64: 840-55.
  65. Frisdal E and Le Goff W. Adipose ABCG1: A potential therapeutic target in obesity? Adipocyte. 2015; 4: 315-8.
  66. Feriel J, Adamo F, Monneret D, Trehel-Tursis V, Favard S, Tse C, Puybasset L, Bonnefont-Rousselot D and Imbert-Bismut F. S100B protein concentration measurement according to two different immunoassaysClin Chem Lab Med. 2015; 53: e169-71.
  67. El Khoury P, Ghislain M, Villard EF, Le Goff W, Lascoux-Combe C, Yeni P, Meyer L, Vigouroux C, Goujard C and Guerin M. Plasma cholesterol efflux capacity from human THP-1 macrophages is reduced in HIV-infected patients: impact of HAARTJournal of lipid research. 2015; 56: 692-702.
  68. Dutilleul C, Chavarria H, Reze N, Sotta B, Baudouin E and Guillas I. Evidence for ACD5 ceramide kinase activity involvement in Arabidopsis response to cold stressPlant Cell Environ. 2015; 38: 2688-97.
  69. Du XM, Kim MJ, Hou L, Le Goff W, Chapman MJ, Van Eck M, Curtiss LK, Burnett JR, Cartland SP, Quinn CM, Kockx M, Kontush A, Rye KA, Kritharides L and Jessup W. HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol exportCirc Res. 2015;116:1133-42.
  70. Charniot JC, Bittar R, Bruckert E and Bonnefont-Rousselot D. Giant xanthomas associated with severe mixed dyslipidemia and arteriosclerotic vascular disease: A case reportJ Clin Lipidol. 2015; 9: 406-10.
  71. Bouchareychas L, Pirault J, Saint-Charles F, Deswaerte V, Le Roy T, Jessup W, Giral P, Le Goff W, Huby T, Gautier EL and Lesnik P. Promoting macrophage survival delays progression of pre-existing atherosclerotic lesions through macrophage-derived apoECardiovasc Res. 2015; 108: 111-23.
  72. Anjani K, Lhomme M, Sokolovska N, Poitou C, Aron-Wisnewsky J, Bouillot JL, Lesnik P, Bedossa P, Kontush A, Clement K, Dugail I and Tordjman J. Circulating phospholipid profiling identifies portal contribution to NASH signature in obesityJournal of hepatology. 2015; 62: 905-12.