Team headed by Philippe Charron Team 1 focuses its research program on 4 research axes : To identify key-players (rare and frequent genetic variants, signaling pathways) in cardiomyopathies and channelopathies through genomics and omics approaches. To understand function, interactions and pathophysiology of key-players in these diseases through human cardiomyocytes (derived from iPS patients) and murine … Lire la suite
Team headed by J.P. Collet The main goal of team 2 is to improve knowledge in cardiovascular medicine, from treatment strategies to education for primary prevention mainly in the field of atherothrombosis. Expanding of the group led to new areas of investigation including now cardiovascular epidemiology, education but also new technologies. Our cardiovascular research is … Lire la suite
Team 3 is headed by Elise Balse and Sophie Nadaud Cardiovascular diseases are often intricate diseases that share pathophysiological mechanisms. Remodeling processes are associated with complex rearrangement at the tissue and at the cellular levels. Team 3 aims at identifying the drivers of the molecular and cellular plasticity that characterize cardiovascular remodeling during heart rhythm … Lire la suite
Team headed by Wilfried Le Goff Team 4 focuses its research on cellular and systemic lipid and lipoprotein metabolism which opens up new insights based its recent pioneer works on the identification by Omic approaches of lipid networks controlling biological activities of atheroprotective HDL and cell activation in cardiometabolic diseases. In the last few years, … Lire la suite
Team headed by Philippe Lesnik Team 5 focuses is focused on the study of mononuclear phagocytes in the context of cardiometabolic diseases. The team main objective is to better understand how different mononuclear phagocytes subsets impact on chronic metabolic disorders, with particular emphasis on macrophages and dendritic cells. To this aim, unique mouse models and … Lire la suite