Publications éq.1

Téléchargement de la liste de publications de l’équipe 1 entre 2012 et 2017:

 

Publications 2014-2017 de l’équipe 1

  1. Esslinger U, Garnier S, Korniat A, Proust C, Kararigas G, Müller-Nurasyid M, Empana JP, Morley MP, Perret C, Stark K, Bick AG, Prasad SK, Kriebel J, Li J, Tiret L, Strauch K, O’Regan DP, Marguiles KB, Seidman JG, Boutouyrie P, Lacolley P, Jouven X, Hengstenberg C, Komajda M, Hakonarson H, Isnard R, Arbustini E, Grallert H, Cook SA, Seidman CE, Regitz-Zagrosek V, Cappola TP, Charron P, Cambien F, Villard E. Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy. PLoS One. 2017 Mar 15;12(3).
  2. Saultier P, Vidal L, Canault M, Bernot D, Falaise C, Pouymayou C, Bordet JC, Saut N, Rostan A, Baccini V, Peiretti F, Favier M, Lucca P, Deleuze JF, Olaso R, Boland A, Morange PE, Gachet C, Malergue F, Fauré S, Eckly A, Trégouët DA, Poggi M, Alessi MC. Macrothrombocytopenia and dense granule deficiency associated with FLI1 variants: ultrastructural and pathogenic features. Haematologica. 2017 Mar 2.
  3. Sennblad B, Basu S, Mazur J, Suchon P, Martinez-Perez A, van Hylckama Vlieg A, Truong V, Li Y, Gådin JR, Tang W, Grossman V, de Haan HG, Handin N, Silveira A, Souto JC, Franco-Cereceda A, Morange PE, Gagnon F, Soria JM, Eriksson P, Hamsten A, Maegdefessel L, Rosendaal FR, Wild P, Folsom AR, Trégouët DA, Sabater-Lleal M. Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levelsHum Mol Genet. 2017 Jan 4.
  4. Fujii Y, Itoh H, Ohno S, Murayama T, Kurebayashi N, Aoki H, Blancard M, Nakagawa Y, Yamamoto S, Matsui Y, Ichikawa M, Sonoda K, Ozawa T, Ohkubo K, Watanabe I, Guicheney P, Horie M. A type 2 ryanodine receptor variant associated with reduced Ca2+ release and short-coupled torsade de pointe ventricular arrhythmiaHeart Rhythm. 2017 Jan;14(1):98-107.
  5. Fraysse B, Guicheney P, Bitoun M. Calcium homeostasis alterations in a mouse model of the Dynamin 2-related centronuclear myopathyBiol Open. 2016 Nov 15;5(11):1691-1696. 
  6. Veselka J, Anavekar NS, Charron P. Hypertrophic obstructive cardiomyopathyLancet. 2016 Nov 30.
  7. Kumar S, Baldinger SH, Gandjbakhch E, Maury P, Sellal JM, Androulakis AF, Waintraub X, Charron P, Rollin A, Richard P, Stevenson WG, Macintyre CJ, Ho CY, Thompson T, Vohra JK, Kalman JM, Zeppenfeld K, Sacher F, Tedrow UB, Lakdawala NK. Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation CarriersJ Am Coll Cardiol. 2016 Nov 29;68(21):2299-2307.
  8. Bruzelius M, Iglesias MJ, Hong MG, Sanchez-Rivera L, Gyorgy B, Souto JC, Frånberg M, Fredolini C, Strawbridge RJ, Holmström M, Hamsten A, Uhlén M, Silveira A, Soria JM, Smadja DM, Butler LM, Schwenk JM, Morange PE, Trégouët DA, Odeberg J. PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics studyBlood. 2016 Oct 14.
  9.  Touat-Hamici Z, Weidmann H, Blum Y, Proust C, Durand H, Iannacci F, Codoni V, Gaignard P, Thérond P, Civelek M, Karabina AS, Lusis AJ, Cambien F, Ninio E. Role of lipid phosphate phosphatase 3 (LPP3) in human aortic endothelial cell function. Cardiovasc Res. 2016 Sep 30.
  10. Codoni V, Blum Y, Civelek M, Proust C, Franzén O, Björkegren JL, Le Goff W, Cambien F, Lusis AJ, Trégouët DA. Preservation analysis of macrophage gene co-expression between human and mouse identifies PARK2 as a genetically controlled
master regulator of oxydative phosphorylation in humans. Genes/Genomes/Genetics 2016 Aug 24.
  11. Suchon P, Frouh FA, Ibrahim M,  Venton G,  Trégouët DA, Morange PE. Genetic risk factors for venous thrombosis in women under combined oral contraceptives. Clin Genet. 2016 Jul 14.
  12. Itoh H, Berthet M, Fressart V, Denjoy I, Maugenre S, Klug D, Mizusawa Y, Makiyama T, Hofman N, Stallmeyer B, Zumhagen S, Shimizu W, Wilde AA, Schulze-Bahr E, Horie M, Tezenas du Montcel S, Guicheney P, Asymmetry of parental origin in long QT syndrome: preferential maternal transmission of KCNQ1 variants linked to channel dysfunction. Eur J Hum Genet. 2016, 24: 1160-1166.
  13. Ojeda FM, Müller C, Börnigen D, Trégouët DA, Schillert A, Heinig M, Zeller T, Schnabel RB. Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events. Genomics Proteomics Bioinformatics. 2016 May 17.
  14. Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators. Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. New Engl J Med 2016, March 24, 2016DOI: 10.1056.
  15. Barthélémy O, Montalescot G. Moving Toward Eradication of Stent ThrombosisJ Am Coll Cardiol. 2016 Feb 23;67(7):763-5.
  16. Silvain J, Kerneis M, Montalescot GPotent P2Y12 Inhibitors in Low-Risk Patients: Is There a Medical Need? J Am Coll Cardiol. 2016 Feb 16;67(6):614-7.
  17. Collet JP, Silvain J, Kerneis M, Cuisset T, Meneveau N, Boueri Z, Barthélémy O, Rangé G, Cayla G, Belle EV, Elhadad S, Carrié D, Caussin C, Rousseau H, Aubry P, Monségu J, Sabouret P, O’Connor SA, Abtan J, Saint-Etienne C, Beygui F, Vicaut E, Montalescot G; ARCTIC Investigators. Clinical Outcome of First- vs Second-Generation DES According to DAPT Duration: Results of ARCTIC-GenerationClin Cardiol. 2016 Feb 16.
  18. Hinds DA, Buil A, Ziemek D, Martinez-Perez A, Malik R, Folkersen L, Germain M, Mälarstig A, Brown A, Soria JM, Dichgans M, Bing N, Franco-Cereceda A, Souto JC, Dermitzakis ET, Hamsten A, Worrall BB, Tung JY; METASTROKE Consortium, INVENT Consortium, Sabater-Lleal M. Genome-wide association analysis of self-reported events in 6,135 individuals and 252,827 controls identifies 8 loci associated with thrombosisHum Mol Genet. 2016 Feb 9.
  19. Liu Z, Silvain J, Kerneis M, Barthélémy O, Payot L, Choussat R, Sabouret P, Cohen M, Pollack CV Jr, Goldstein P, Zeymer U, Huber K, Vicaut E, Collet JP, Montalescot G. Intravenous Enoxaparin Versus Unfractionated Heparin in Elderly Patients Undergoing Primary Percutaneous Coronary Intervention: An Analysis of the Randomized ATOLL TrialAngiology. 2016 Feb 9.
  20. Thiele H, Desch S, Piek JJ, Stepinska J, Oldroyd K, Serpytis P, Montalescot G, Noc M, Huber K, Fuernau G, de Waha S, Meyer-Saraei R, Schneider S, Windecker S, Savonitto S, Briggs A, Torremante P, Vrints C, Schuler G, Ceglarek U, Thiery J, Zeymer U; CULPRIT-SHOCK Investigators. Multivessel versus culprit lesion only percutaneous revascularization plus potential staged revascularization in patients with acute myocardial infarction complicated by cardiogenic shock: Design and rationale of CULPRIT-SHOCK trialAm Heart J. 2016 Feb;172:160-9.
  21. Pinto YM, Elliott PM, Arbustini E, Adler Y, Anastasakis A, Böhm M, Duboc D, Gimeno J, de Groote P, Imazio M, Heymans S, Klingel K, Komajda M, Limongelli G, Linhart A, Mogensen J, Moon J, Pieper PG, Seferovic PM, Schueler S, Zamorano JL, Caforio AL, Charron P. Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases. Eur Heart J. 2016 Jan 19.
  22. Marchand A, Atassi F, Mougenot N, Clergue M, Codoni V, Berthuin J, Proust C, Trégouët DA, Hulot JS, Lompré AM. miR-322 regulates insulin signaling pathway and protects against metabolic syndrome-induced cardiac dysfunction in mice. Biochim Biophys Acta. 2016.
  23. Itoh H, Crotti L, Aiba T, Spazzolini C, Denjoy I, Fressart V, Hayashi K, Nakajima T, Ohno S, Makiyama T, Wu J, Hasegawa K, Mastantuono E, Dagradi F, Pedrazzini M, Yamagishi M, Berthet M, Murakami Y, Shimizu W, Guicheney P, Schwartz PJ, Horie M. The genetics underlying acquired long QT syndrome: impact for genetic screening. Eur Heart J. 2015.
  24. Itoh H, Berthet M, Fressart V, Denjoy I, Maugenre S, Klug D, Mizusawa Y, Makiyama T, Hofman N, Stallmeyer B, Zumhagen S, Shimizu W, Wilde AA, Schulze-Bahr E, Horie M, Tezenas du Montcel S, Guicheney P. Asymmetry of parental origin in long QT syndrome: preferential maternal transmission of KCNQ1 variants linked to channel dysfunctionEur J Hum Genet. 2015.
  25. Arslan-Kirchner M, Arbustini E, Boileau C, Charron P, Child AH, Collod-Beroud G, De Backer J, De Paepe A, Dierking A, Faivre L, Hoffjan S, Jondeau G, Keyser B, Loeys B, Mayer K, Robinson PN, Schmidtke J. Clinical utility gene card for: Hereditary thoracic aortic aneurysm and dissection including next-generation sequencing-based approaches. Eur J Hum Genet. 2016 Jan;24(1).
  26. Elliott P*, Charron P*, Blanes JR, Tavazzi L, Tendera M, Konté M, Laroche C, Maggioni AP; EORP Cardiomyopathy Registry Pilot Investigators. European Cardiomyopathy Pilot Registry: EURObservational Research Programme of the European Society of CardiologyEur Heart J. 2016 Jan 7;37(2):164-73. *equal first author
  27. De Vries PS, Chasman DI, Sabater-Lleal M, et al. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Hum Mol Genet. 2016; 25(2): 358-70.
  28. Suchon P, Al Frouh F, Henneuse A, Ibrahim M, Brunet D, Barthet MC, Aillaud MF, Venton G, Alessi MC, Trégouët DA, Morange PE. Risk factors for venous thromboembolism in women under combined oral contraceptive. The PIL Genetic RIsk Monitoring (PILGRIM) Study. Thromb Haemost. 2015; 115(1): 135-42.
  29. Itoh H, Dochi K, Shimizu W, Denjoy I, Ohno S, Aiba T, Kimura H, Kato K, Fukuyama M, Hasagawa K, Schulze-Bahr E, Guicheney P, Horie M. A Common Mutation of Long QT Syndrome Type 1 in Japan. Circ J. 2015; 79(9): 2026-30.
  30. Morange PE, Suchon P, Trégouët DA. Genetics of Venous Thrombosis: update in 2015Thromb Haemost. 2015; 114(5): 910-9.
  31. Hankiewicz K, Carlier RY, Lazaro L, Linzoain J, Barnerias C, Gómez-Andrés D, Avila-Smirnow D, Ferreiro A, Estournet B, Guicheney P, Germain DP, Richard P, Bulacio S, Mompoint D, Quijano-Roy S. Whole-body muscle magnetic resonance imaging in SEPN1-related myopathy shows a homogeneous and recognizable pattern. Muscle Nerve. 2015; 52(5): 728-35.
  32. Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, Schadt EE, Yang X, Samani NJ, Björkegren JL, Erdmann J, Schunkert H, Lusis AJ; Leducq Consortium CAD Genomics. Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arterioscler Thromb Vasc Biol. 2015; 35(10): 2207-17.
  33. Weidmann H, Touat-Hamici Z, Durand H, Mueller C, Chardonnet S, Pionneau C, Charlotte F, Janssen KP, Verdugo R, Cambien F, Blankenberg S, Tiret L, Zeller T, Ninio E. SASH1, a new potential link between smoking and atherosclerosis. Atherosclerosis. 2015; 242(2): 571-9.
  34. Karabina S, Ninio E. Plasma PAFAH/PLA2G7 Genetic Variability, Cardiovascular Disease, and Clinical Trials. Enzymes. 2015; 38: 145-55.
  35. Zeller T, Haase T, Müller C, Riess H, Lau D, Zeller S, Krause J, Baumert J, Pless O, Dupuis J, Wild PS, Eleftheriadis M, Waldenberger M, Zeilinger S, Ziegler A, Peters A, Tiret L, Proust C, Marzi C, Munzel T, Strauch K, Prokisch H, Lackner KJ, Herder C, Thorand B, Benjamin EJ, Blankenberg S, Koenig W, Schnabel RB. Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels. Circ Cardiovasc Genet. 2015; 8(5): 717-26.
  36. Proust C, Empana JP, Boutouyrie P, Alivon M, Challande P, Danchin N, Escriou G, Esslinger U, Laurent S, Li Z, Pannier B, Regnault V, Thomas F, Jouven X, Cambien F, Lacolley P. Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Circ Cardiovasc Genet. 2015; 8(4): 628-36.
  37. Christensen AH, Kamstrup PR, Gandjbakhch E, Benn M, Jensen JS, Bundgaard H, Villard E, Tybjærg-Hansen A. Plakophilin-2 c.419C>T and risk of heart failure and arrhythmias in the general population. Eur J Hum Genet. 2015.
  38. Behr ER, Savio-Galimberti E, Barc J, et al. Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study. Cardiovasc Res. 2015; 106(3): 520-9.
  39. Christofidou P, Nelson CP, Nikpay M, Qu L, Li M, Loley C, Debiec R, Braund PS, Denniff M, Charchar FJ, Arjo AR, Trégouët DA, Goodall AH, Cambien F, Ouwehand WH, Roberts R, Schunkert H, Hengstenberg C, Reilly MP, Erdmann J, McPherson R, König IR, Thompson JR, Samani NJ, Tomaszewski M. Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages. Am J Hum Genet. 2015; 97(2): 228-37.
  40. Poitou C, Perret C, Mathieu F, Truong V, Blum Y, Durand H, Alili R, Chelghoum N, Pelloux V, Aron-Wisnewsky J, Torcivia A, Bouillot JL, Parks BW, Ninio E, Clément K, Tiret L. Bariatric Surgery Induces Disruption in Inflammatory Signaling Pathways Mediated by Immune Cells in Adipose Tissue: A RNA-Seq Study. PLoS One. 2015; 10(5): e0125718
  41. Haas J, Frese KS, Peil B, et al. Atlas of the clinical genetics of human dilated cardiomyopathy. Eur Heart J. 2015; 36(18): 1123-35a.
  42. Hägg S, Fall T, Ploner A, et al; European Network for Genetic and Genomic Epidemiology Consortium. Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. Int J Epidemiol. 2015; 44(2): 578-86.
  43. Guardiola M, Exeter HJ, Perret C, Folkersen L, Van’t Hooft F, Eriksson P, Franco-Cereceda A, Paulsson-Berne G, Palmen J, Li K, Cooper JA, Khaw KT, Mallat Z, Ninio E, Karabina SA, Humphries SE, Boekholdt SM, Holmes MV, Talmud PJ. PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk. Circ Cardiovasc Genet. 2015; 8(2): 356-62.
  44. Garnier S, Hengstenberg C, Lamblin N, Dubourg O, De Groote P, Fauchier L, Trochu JN, Arbustini E, Esslinger U, Barton PJ, Meder B, Katus H, Frese K, Komajda M, Cook SA, Isnard R, Tiret L, Villard E, Charron P. Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients. Int J Cardiol. 2015; 189: 105-7.
  45. Dennis J, Kassam I, Morange PE, Trégouët DA, Gagnon F. Genetic determinants of tissue factor pathway inhibitor plasma levels. Thromb Haemost. 2015; 114(2): 245-57.
  46. Nelson CP, Hamby SE, Saleheen D, et al; CARDIoGRAM+C4D Consortium. Genetically determined height and coronary artery disease. N Engl J Med. 2015; 372(17): 1608-18.
  47. Germain M, Chasman DI, de Haan H, et al. Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism. Am J Hum Genet. 2015; 96(4): 532-42.
  48. Lemire M, Zaidi SH, Ban M, Ge B, Aïssi D, Germain M, Kassam I, Wang M, Zanke BW, Gagnon F, Morange PE, Trégouët DA, Wells PS, Sawcer S, Gallinger S, Pastinen T, Hudson TJ. Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci. Nat Commun. 2015; 6: 6326.
  49. Fall T, Hägg S, Ploner A, Mägi R, et al; ENGAGE Consortium. Age- and sex-specific causal effects of adiposity on cardiovascular risk factors. Diabetes. 2015; 64(5): 1841-52.
  50. Rocañín-Arjó A, Dennis J, Suchon P, Aïssi D, Truong V, Trégouët DA, Gagnon F, Morange PE. Thrombin generation potential and whole-blood DNA methylation. Thromb Res. 2015; 135(3): 561-4.
  51. Locke AE, Kahali B, Berndt SI, et al. Genetic studies of body mass inex yield new insights for obesity biology. Nature. 2015; 518(7538): 197-206.
  52. Shungin D, Winkler TW, Croteau-Chonka DC, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015; 518(7538): 187-96.
  53. Liu A, Ming JY, Fiskesund R, Ninio E, Karabina SA, Bergmark C, Frostegård AG, Frostegård J. Induction of dendritic cell-mediated T-cell activation by modified but not native low-density lipoprotein in humans and inhibition by annexin a5: involvement of heat shock proteins. Arterioscler Thromb Vasc Biol. 2015 Jan; 35(1): 197-205.
  54. Baumert J, Huang J, McKnight B, et al. No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS One. 2014; 9(12): e111156.
  55. Germain M, Pezzolesi MG, Sandholm N, McKnight AJ, Susztak K, Lajer M, Forsblom C, Marre M, Parving HH, Rossing P, Toppila I, Skupien J, Roussel R, Ko YA, Ledo N, Folkersen L, Civelek M, Maxwell AP, Tregouet DA, Groop PH, Tarnow L, Hadjadj S. SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes. Diabetologia. 2015; 58(3): 543-8.
  56. Soria JM, Morange PE, Vila J, Souto JC, Moyano M, Trégouët DA, Mateo J, Saut N, Salas E, Elosua R. Multilocus genetic risk scores for venous thromboembolism risk assessment. J Am Heart Assoc. 2014; 3(5): e001060
  57. Tsaprouni LG, Yang TP, Bell J, Dick KJ, Kanoni S, Nisbet J, Viñuela A, Grundberg E, Nelson CP, Meduri E, Buil A, Cambien F, Hengstenberg C, Erdmann J, Schunkert H, Goodall AH, Ouwehand WH, Dermitzakis E, Spector TD, Samani NJ, Deloukas P. Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation. Epigenetics. 2014; 9(10): 1382-96.
  58. Adoue V, Schiavi A, Light N, Almlöf JC, Lundmark P, Ge B, Kwan T, Caron M, Rönnblom L, Wang C, Chen SH, Goodall AH, Cambien F, Deloukas P, Ouwehand WH, Syvänen AC, Pastinen T. Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs. Mol Syst Biol. 2014; 10: 754.
  59. Béziau DM, Barc J, O’Hara T, Le Gloan L, Amarouch MY, Solnon A, Pavin D, Lecointe S, Bouillet P, Gourraud JB, Guicheney P, Denjoy I, Redon R, Mabo P, le Marec H, Loussouarn G, Kyndt F, Schott JJ, Probst V, Baró I. Complex Brugada syndrome inheritance in a family harbouring compound SCN5A and CACNA1C mutations. Basic Res Cardiol. 2014; 109(6): 446.
  60. Inamori K, Willer T, Hara Y, Venzke D, Anderson ME, Clarke NF, Guicheney P, Bönnemann CG, Moore SA, Campbell KP. Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues. J Biol Chem. 2014; 289(41): 28138-48.
  61. Makita N, Yagihara N, Crotti L, et al. Novel calmodulin mutations associated with congenital arrhythmia susceptibility. Circ Cardiovasc Genet. 2014; 7(4): 466-74.
  62. Ziyadeh-Isleem A, Clatot J, Duchatelet S, Gandjbakhch E, Denjoy I, Hidden-Lucet F, Hatem S, Deschênes I, Coulombe A, Neyroud N, Guicheney P. A truncating SCN5A mutation combined with genetic variability causes sick sinus syndrome and early atrial fibrillation. Heart Rhythm. 2014; 11(6): 1015-23.
  63. Hoggart CJ, Venturini G, Mangino M, et al. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genet. 2014; 10(7): e1004508.
  64. Almlöf JC, Lundmark P, Lundmark A, Ge B, Pastinen T; Cardiogenics Consortium, Goodall AH, Cambien F, Deloukas P, Ouwehand WH, Syvänen AC. Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes. PLoS One. 2014; 9(7): e102612.
  65. Beygui F, Wild PS, Zeller T, Germain M, Castagné R, Lackner KJ, Münzel T, Montalescot G, Mitchell GF, Verwoert GC, Tarasov KV, Trégouët DA, Cambien F, Blankenberg S, Tiret L. Adrenomedullin and arterial stiffness: integrative approach combining monocyte ADM expression, plasma MR-Pro-ADM, and genome-wide association study. Circ Cardiovasc Genet. 2014; 7(5): 634-41.
  66. Canault M, Ghalloussi D, Grosdidier C, Guinier M, Perret C, Chelghoum N, Germain M, Raslova H, Peiretti F, Morange PE, Saut N, Pillois X, Nurden AT, Cambien F, Pierres A, van den Berg TK, Kuijpers TW, Alessi MC, Tregouet DA. Human CalDAG-GEFI gene (RASGRP2) mutation affects platelet function and causes severe bleeding. J Exp Med. 2014; 211(7): 1349-62.
  67. Gagnon F, Aïssi D, Carrié A, Morange PE, Trégouët DA. Robust validation of methylation levels association at CPT1A locus with lipid plasma levels. J Lipid Res. 2014; 55(7): 1189-1191.
  68. Aschard H, Vilhjálmsson BJ, Greliche N, Morange PE, Trégouët DA, Kraft P. Maximizing the power of principal-component analysis of correlated phenotypes in genome-wide association studies. Am J Hum Genet. 2014; 94(5): 662-76.
  69. Bruzelius M, Strawbridge RJ, Trégouët DA, Wiggins KL, Gertow K, Sabater-Lleal M, Öhrvik J, Bergendal A, Silveira A, Sundström A, Kieler H, Syvänen AC, Smith NL, Morange PE, Odeberg J, Hamsten A. Influence of coronary artery disease-associated genetic variants on risk of venous thromboembolism. Thromb Res. 2014; 134(2): 426-32.
  70. Maia J, Gomes TN, Trégouët DA, Katzmarzyk PT. Familial resemblance of physical activity levels in the Portuguese population. J Sci Med Sport. 2014; 17(4): 381-6.
  71. Dick KJ, Nelson CP, Tsaprouni L, Sandling JK, Aïssi D, Wahl S, Meduri E, Morange PE, Gagnon F, Grallert H, Waldenberger M, Peters A, Erdmann J, Hengstenberg C, Cambien F, Goodall AH, Ouwehand WH, Schunkert H, Thompson JR, Spector TD, Gieger C, Trégouët DA, Deloukas P, Samani NJ. DNA methylation and body-mass index: a genome-wide analysis. Lancet. 2014; 383(9933): 1990-8.
  72. Huang J, Huffman JE, Yamakuchi M, et al; CHARGE Consortium Hemostatic Factor Working Group. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 2014; 34(5): 1093-101.
  73. Meder B, Rühle F, Weis T, et al. A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy. Eur Heart J. 2014; 35(16): 1069-77.
  74. Cohen W, Castelli C, Suchon P, Bouvet S, Aillaud MF, Brunet D, Barthet MC, Alessi MC, Trégouët DA, Morange PE. Risk assessment of venous thrombosis in families with known hereditary thrombophilia: the MARseilles-NImes prediction model. J Thromb Haemost. 2014; 12(2): 138-46.
  75. Rocanin-Arjo A, Cohen W, Carcaillon L, Frère C, Saut N, Letenneur L, Alhenc-Gelas M, Dupuy AM, Bertrand M, Alessi MC, Germain M, Wild PS, Zeller T, Cambien F, Goodall AH, Amouyel P, Scarabin PY, Trégouët DA, Morange PE; CardioGenics Consortium. A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential. Blood. 2014; 123(5): 777-85.
  76. Eyries M, Montani D, Girerd B, Perret C, Leroy A, Lonjou C, Chelghoum N, Coulet F, Bonnet D, Dorfmüller P, Fadel E, Sitbon O, Simonneau G, Tregouët DA, Humbert M, Soubrier F. EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension. Nat Genet. 2014; 46(1): 65-9.